Gatifloxacin Impurity A HCl (USP)
1-Cyclopropyl-6-fluoro-8-hydroxy-7-(3-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- CAS RN:
- Mol Formula: C18H21ClFN3O4
- Mol Weight: 397.84
Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Fluoroquinolones are broad-spectrum antibiotics, effective for both gram-negative and gram-positive bacteri, that play an important rolein treatment of serious bacterial infections, especially hospital-acquired infections and others in which resistance to older antibacterial classesis suspected. Gatifloxacin is used for the treatment of respiratory tract infections, it was also produced it in eye-drop formulation. In many countries, gatifloxacin is also available as tablets and in various aqueous solutions for intravenous therapy.
We have successfully synthesized impurities of the Gatifloxacin. This will be of interest to pharmaceutical companies and analytical labs.