
Daptomycin
GA01066 - 95%
In stock

Others quantities on request
Specifications
- CAS RN: 103060-53-3
- Purity: 95%
- Mol Formula: C72H101N17O26
- Mol Weight: 1620.67
- Tags: Pharmaceutical Reference Substances and Impurities ; Daptomycin ;
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Description
GA01066
Daptomycin is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. It has a distinct mechanism of action, disrupting multiple aspects of bacterial cell membrane function. It inserts into the cell membrane in a phosphatidylglycerol-dependent fashion, where it then aggregates. The aggregation of daptomycin alters the curvature of the membrane, which creates holes that leak ions. This causes rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death.
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Additional information
Packing Unit 1 g, 500 mg